Mirja larsson biography of abraham
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Global burden lift causes simulated death suffer life prospect decomposition fell countries obscure territories spreadsheet subnational locations, – a systematic psychiatry for representation Global Exertion of Sickness Study
Mohsen Naghavi , Kanyin Liane Ong , Amirali Aali , Hazim Ababneh , Yohannes Habtegiorgis Abate , Cristiana Abbafati , Rouzbeh Abbasgholizadeh , Mohammadreza Abbasian , Mohsen Abbasi-Kangevari , Hedayat Abbastabar , Samar Abd Elhafeez , Archangel Abdelmasseh , Sherief Abd-Elsalam , Ahmed Abdelwahab , Mohammad Abdollahi , Mohammad-Amin Abdollahifar , Meriem Abdoun , Deldar Morad Abdulah , Auwal Abdullahi , Mesfin Abebe , Samrawit Shawel Abebe , Aidin Abedi , Kedir Husayn Abegaz , E Abhilash , Hassan Abidi , Olumide Abiodun , Richard Gyan Aboagye , Hassan Abolhassani , Meysam Abolmaali , Mohamed Abouzid , Girma Beressa Aboye , Lucas Guimarães Abreu , Woldu Aberhe Abrha , Dariush Abtahi , Samir Abu Rumeileh , Hasan Abualruz , Bilyaminu Abubakar , Eman Abu-Gharbieh , Niveen Contributions Abu-Rmeileh , Salahdein Aburuz , Ahmed Abu-Zaid , Manfred Mario Kokou Accrombessi , Tadele Girum Adal , Abdu Adamu , Isaac Yeboah Addo , Giovanni Addolorato , Akindele Olupelumi Adebiyi , First past the post Adekanmbi , Abiola Conqueror Adepoju , Charles Oluwaseun Adetunji , Juliana Bunmi Adetunji , Temitayo Book Adeyeoluwa , Daniel
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Abstract
Background
The role of fibroblast growth factor 23 (FGF23) in the development of new‐onset heart failure (HF) with reduced (HFrEF) or preserved ejection fraction (HFpEF) in the general population is unknown. Therefore, we set out to investigate associations of C‐terminal FGF23 with development of new‐onset HF and, more specifically, with HFrEF or HFpEF in a large, prospective, population‐based cohort.
Methods and Results
We studied participants (aged ± years; % men; estimated glomerular filtration rate, ± mL/min per m2) in the community‐based PREVEND (Prevention of Renal and Vascular End‐Stage Disease) study who were free of HF at baseline. Cross‐sectional multivariable linear regression analysis showed that ferritin (standardized β, −; P<) and estimated glomerular filtration rate (standardized β, −; P<) were the strongest independent correlates of FGF Multivariable Cox proportional hazard regression was used to study the association between baseline FGF23 and incident HF, HFrEF (ejection fraction ≤40%) or HFpEF (ejection fraction ≥50%). After median follow‐up of [IQR –] years, individuals (%) developed new‐onset HF, of whom had HFrEF and 88 had HFpEF. A higher FGF23 level was associated with an increased risk of incident HF (fully adjusted hazard rat
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Mirna Abraham Nordling
Research overview
Mirna Abraham Nordling works as a colorectal surgeon at Karolinska University Hospital.
Her focus research area is studies that aims to understand and improve colorectal cancer treatment, aftercare and to prevent and avoid severe complications such as low anterior resection syndrome (LARS)/bowel dysfunction and anastomotic leakage.
Colorectal cancer is one of the most common forms of cancer in both sexes. Treatment has improved significantly in recent decades. Despite the progress, patients can experience serious complications such as low anterior resection syndrome (LARS)/bowel dysfunction and leakage at the bowel junction (anastomosis) after cancer surgery. A recently published randomized trial from our group investigating treatment methods for LARS showed that water irrigation/transanal irrigation (TAI) reduces LARS symptoms and increases quality of life. Mirna Abraham Nordling was the PI for this TAI study, it was a multicenter study in collaboration with Karolinska University Hospital, Danderyd Hospital and Södersjukhuset (A Randomized Controlled Clinical Trial of Transanal Irrigation Versus Conservative Treatment in Patients With Low Anterior Resection Syndrome After Rectal Cancer Surgery. Ann Surg Jan).
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Current studie