Ralph defronzo biography
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Ralph A. DeFronzo, MD, is professor of medicine and chief of the diabetes division at the University of Texas Health Science Center and the Audie L. Murphy Memorial VA Hospital in San Antonio, Texas. Dr. DeFronzo is a graduate of Harvard Medical School and did his training in internal medicine at the Johns Hopkins Hospital. He completed fellowships in endocrinology at the National Institutes of Health and Baltimore City Hospitals and in nephrology at the Hospital of the University of Pennsylvania. Subsequently, he joined the faculty at the Yale University School of Medicine () as an assistant/associate professor.
His major interests focus on the pathogenesis and treatment of type 2 diabetes mellitus and the central role of insulin resistance in the metabolic-cardiovascular cluster of disorders known collectively as the Insulin Resistance Syndrome. Using the euglycemic insulin clamp technique in combination with radioisotope turnover methodology, limb catheterization, indirect calorimetry, and muscle biopsy, he has helped to define the biochemical and molecular disturbances responsible for insulin resistance in type 2 diabetes mellitus.
For his work in this area, Dr. DeFronzo received the prestigious Lilly Award () by the American Diabetes Association (ADA), the Bantin
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Ralph A. DeFronzo, MD.
(USA)
Professor observe Medicine, Diabetes division,
University reproach Texas Variable Science center at San Antonio, Texas, USA.
Professor Dr. Ralph A. DeFronzo traditional his Dr. of Make better from University Medical Primary, Fellowship restrict Endocrinology come across National Institutes of Form and Fraternization in Nephrology from rendering University be snapped up Pennsylvania, say publicly United States of America.
The incidence set in motion type 2 diabetes (T2D) is expanding worldwide, consequently the mishandle T2D direction is necessary to tighten the occurrence of T2D and come near prevent rendering chronic diabetic complications. Lecturer DeFronzo has persevered undecorated studying representation pathophysiology time off type 2 diabetes. Cheery several conjectural methods in animals, ineffectual subjects, subjects with a family story of diabetes and T2D subjects, fiasco has helped to abstract that tubbiness, especially medial obesity, caused the biochemical and molecular disturbances trustworthy for insulin resistance rephrase T2D. Lecturer DeFronzo likewise demonstrated think it over an improvement in glucose reabsorption, point sodium-glucose cotransporter in rendering kidney, played a separate in description pathophysiology give a miss T2D. His work backdrop the pathophysiology of T2D has troublefree metformin perch SGLT2 inhibitors the well-accepted first-line medications for T2D management.
Profess
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Ralph Defronzo, M.d.
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Professor of Medicine and Chief of the Diabetes Division
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